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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLNK All Species: 14.55
Human Site: T289 Identified Species: 35.56
UniProt: Q7Z7G1 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z7G1 NP_443196.2 428 49554 T289 N I L P Y K Y T S W R P P F P
Chimpanzee Pan troglodytes XP_520687 428 49546 T289 N I L P Y K Y T S W R P S F P
Rhesus Macaque Macaca mulatta XP_001098116 428 49645 T289 N I P P Y K Y T S W R P P F P
Dog Lupus familis XP_545941 442 51119 T303 N L L H Y K N T S W R K P S P
Cat Felis silvestris
Mouse Mus musculus Q9QZE2 435 49473 T289 R M L P Y E N T N S E K P D P
Rat Rattus norvegicus Q4KM52 457 50615 V292 S S H R Q D T V Q S P V F P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508906 530 59405 N336 A L P P F N S N T F P S R T T
Chicken Gallus gallus Q9YGC1 552 61805 N350 R A L K K T S N A V N P A K P
Frog Xenopus laevis NP_001085767 508 56853 F364 P G N M N R S F S E G T C N G
Zebra Danio Brachydanio rerio XP_001343678 405 45344 F270 N M Q Q M D D F P P P P V E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 91.1 68.5 N.A. 61.3 21.2 N.A. 26.4 26.2 23.4 20.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99 94.8 78.2 N.A. 71.7 38.9 N.A. 41.8 40.7 38.9 36.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 66.6 N.A. 40 6.6 N.A. 6.6 20 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 93.3 73.3 N.A. 60 13.3 N.A. 33.3 26.6 13.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 0 0 10 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 0 0 0 20 10 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 10 0 0 0 10 10 0 0 10 0 % E
% Phe: 0 0 0 0 10 0 0 20 0 10 0 0 10 30 0 % F
% Gly: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 10 % G
% His: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 30 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 10 40 0 0 0 0 0 20 0 10 0 % K
% Leu: 0 20 50 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 20 0 10 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 50 0 10 0 10 10 20 20 10 0 10 0 0 10 0 % N
% Pro: 10 0 20 50 0 0 0 0 10 10 30 50 40 10 70 % P
% Gln: 0 0 10 10 10 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 20 0 0 10 0 10 0 0 0 0 40 0 10 0 0 % R
% Ser: 10 10 0 0 0 0 30 0 50 20 0 10 10 10 0 % S
% Thr: 0 0 0 0 0 10 10 50 10 0 0 10 0 10 10 % T
% Val: 0 0 0 0 0 0 0 10 0 10 0 10 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 40 0 0 0 0 0 % W
% Tyr: 0 0 0 0 50 0 30 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _